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HOUSTON – Asthmatic smokers who switched to electronic cigarettes showed evidence suggestive of respiratory harm reversal in a retrospective pilot study.
“Electronic cigarette use improves respiratory physiology and subjective asthma outcomes in asthmatic smokers. E-cigarettes are a safer alternative to conventional cigarettes in this vulnerable population,” Dr. Cristina Russo declared at the annual meeting of the American Academy of Allergy, Asthma, and Immunology.
She said that her small retrospective study is the first to examine the respiratory health impact of a switch to e-cigarettes by asthmatic smokers.
Every one of the objective and subjective measures of asthma status evaluated in the study showed statistically significant improvement 1 year after patients adopted e-cigarettes, and the e-cigarette users’ consumption of conventional cigarettes dropped precipitously, reported Dr. Russo of the University of Catania (Italy).
She and her colleagues in the university asthma clinic have taken to suggesting the use of battery-powered e-cigarettes to their asthmatic smokers who haven’t benefited from or aren’t interested in trying the more conventional approaches to smoking cessation or reduction, including medications. While abstinence from cigarette smoking is best, the available evidence indicates e-cigarettes are at least 95% less harmful than conventional cigarettes in the general population, she said.
The study included 18 smokers with mild to moderate asthma who switched to e-cigarettes and underwent spirometry and other testing at baseline and 6 and 12 months of follow-up. Ten patients switched over to e-cigarettes exclusively, while the other 8 used both conventional and e-cigarettes.
Among the highlights: The mid-range forced expiratory flow (25%-75%) showed a major, clinically important improvement, increasing from 2.75 L/sec to 3.11 L/sec. And patients’ mean self-reported conventional cigarette consumption dropped from 21.9 per day at baseline to 5 at 6 months and 3.9 per day at 12 months.
|Dr. Cristina Russo|
Among the group at large, no significant change was seen in the frequency of asthma exacerbations resulting in hospitalization. However, among the frequent exacerbators – the six patients with two or more exacerbations during the 6 months prior to baseline – exacerbation frequency was cut in half both 6 and 12 months following the switch to e-cigarettes.
Dr. Russo’s presentation sparked vigorous audience discussion. Several physicians cited a Centers for Disease Control and Prevention warning about the unknowns regarding e-cigarette safety, and one allergist declared he didn’t think physicians should ever encourage patients to smoke anything. But others defended the “lesser of two evils” approach adopted by Dr. Russo and coworkers.
Dr. Russo noted that the prevalence of smoking among asthma patients is similar to that of the general population. She called smoking and asthma “a dangerous liaison.” Smoking accelerates asthma patients’ decline in lung function, worsens persistent airways obstruction, and increases insensitivity to corticosteroids.
Her study was supported by a university grant and the Italian League Against Smoking. She reported having no financial conflicts.
E-cigs Ease Respiratory Harm in Asthmatic Smokers
V8P Juice has decided, after months of mixing and testing flavor combinations, to venture out and put their best eight flavors forward, into the hands of vapers everywhere.
Go to V8P Juice Website www.V8PJuice.com and try some V8P Juice! – Enter Promo code “SPINFUEL” at checkout and receive 2 for the price of 1.
V8P Juice was started by a team of Doctors, Nurse Practitioners, Chemists & Engineers, and is based in Delray Beach, Florida. I think it’s amazing that the medical field is getting involved in actually producing eLiquid. They see the benefits of vaping and wanted to produce flavors and even a magnetic vaping pen to help those who have trouble with gripping and screwing tanks onto pens in order to vape them. There were even more interesting facts that had me intrigued before we tasted the ejuice. V8P Juice is mixed with Non-GMO VG (vegetable glycerin) and plant-based PG (propylene glycol) derived from Non-GMO corn. The Nicotine is NicSelect-a liquid nicotine derived naturally from tobacco plants in a FDA inspected facility. From start to finish, the team and I thoroughly enjoyed the four flavors we were sent to review.
Blonde Bombshell: “Our triple vanilla custard with hints of flan & sweet cream.”
Sweet Geisha: “Our strawberry/vanilla milkshake with sweet cream, it will have you begging for more. “
Royal Blood: “ Our grape/triple berry bubble gum. This will make you kick back and blow clouds.”
Latin Lover: “Our tangerine/mango/sweet mint with hints of kiwi and watermelon-just how she likes it.”
Because this is only the third review from the NEW Spinfuel eLiquid Team Review, we suggest that you take a look at the new protocols we’ve set up for each of the reviews we will do moving forward. You’ll need to know how long we vape the ejuice, in what manner, what we look for, and how an eliquid may earn a coveted Spinfuel Choice Award. In addition, in order to understand the scores and our comments about each one, knowing the intricacies of our methods will give you a greater understanding of the process. Click here:
Nicotine Levels Available: 0mg, 1.5mg, 3mg, 6mg, 12mg, or 18mg
Ratio The V8P Juice is mixed at a 70vg/30pg ratio.
The team and I received the 30ml frosted glass bottles with glass droppers. They were child safe and tamper evident which is always important. The frosted glass is a really nice touch in the overall look for this line. The labels are bright and colorful-they POP and will definitely stand out on a shelf amongst other eLiquids. The glass droppers are actually color-coded per nicotine level, which is an uber cool feature. You always know what mg you are vaping just by the dropper you receive!!
This is what it is all about; the flavor. We have four to cover, and they are presented below. I’m Dori, the head writer, and I will kick off each flavor with my thoughts and then the team will follow with their own. Remember, as always, taste is subjective and is in the mouth of the beholder. I do believe I’ve assembled a truly unique team. We all have different palates and I value each opinion of those on my team. Let’s see what we come up with for these for unique blends of sweet delights!!
We recently reached out to Independent Vape Juice Reviewer & Connoisseur Bella Vapes for her honest input on our signature e-liquids.
Read what she had to say about V8P Juice here. She runs a great website and review board for new juice. We copied some of the review below for ease of use but please go visit here site for the full review.
“Sweet Geisha is our signature Strawberry Milkshake blend.”
Sweet Geisha is a creamy strawberry milkshake flavor. I really enjoyed this flavor. It’s sweet, creamy and full of flavor. Even in a tank at 70vg. I could taste and enjoy it. On inhale I get a sweet vanilla milk flavor and the strawberry comes in as I inhale and on exhale the flavors blend into a delicious strawberry milkshake. Sweet Geisha quickly became my favorite out of the four flavors I was sent to try.
“Latin Lover is our Signature Orange Mango Sweet Mint. A Surprisingly refreshing vape, Tastes a lot like an orange tic tac.”
I primarily get orange and a little mint, with the mango coming through every once in a while. I usually don’t care for orange flavors, but this one is lovely. I think that this is spot on with the orange tic tac description. That’s exactly what it reminded me of. It is a light and refreshing vape, well blended and smooth with a clean finish. I could see this one being all day vapeable.
“Last Samurai is our Signature Watermelon Candy Blend.”
This one I didn’t really care for. I get some watermelon flavor, but it’s not really a watermelon candy flavor like I was expecting. I’m not sure how I’d describe it, it’s not a watermelon jolly rancher, maybe like a light watermelon gummy flavor. It’s not bad, but after vaping it for several hours I still didn’t care for it. That said, even though the flavor wasn’t for me, the quality of the e-liquid was the same as the others I tried. It was smooth, without any traces of harshness.
“King’s Ransom is our Signature Peanut Butter Creme Brulee Custard.”
Kings Ransom is delicious and complex. I get a light flaky danish with a creamy peanut butter on inhale and peanut butter with hints of coconut and caramel on exhale. Other flavor notes come into the mix as I vape it, but the flavor is so well blended it’s hard to pick out what each note is. I really enjoyed this flavor, more so on a dripper than in a tank. On a dripper this flavor shines, I get more of the subtle flavor nuances that didn’t come through in a tank. This is the only one that had a marked difference in flavor when I dripped it vs using it in a tank. I couldn’t get enough of this flavor on the dripper, but the flavor is somewhat muted in a tank.
Overall, I was pretty impressed with the quality of these e-liquids. I found all of them to be pretty flavorful in a tank at 30/70 pg/vg ratio, which was kind of surprising to me as I usually have a hard time tasting e-liquids with that high of a vg level in my tanks. All four flavors were well crafted, smooth and without any harshness. You can taste the quality of the ingredients and time that was put into developing these e-liquids.
HERSHEY, Pa. — E-cigarettes appear to be less addictive than cigarettes for former smokers and this could help improve understanding of how various nicotine delivery devices lead to dependence, according to researchers. “We found that e-cigarettes appear to be less addictive than tobacco cigarettes in a large sample of long-term users,” said Jonathan Foulds, professor of public health sciences and psychiatry, Penn State College of Medicine. The popularity of e-cigarettes, which typically deliver nicotine, propylene glycol, glycerin and flavorings through inhaled vapor, has increased in the past five years. There are currently more than 400 brands of “e-cigs” available. E-cigs contain far fewer cancer-causing and other toxic substances than cigarettes, however their long-term effects on health and nicotine dependence are unknown.
To study e-cigarette dependence, the researchers developed an online survey, including questions designed to assess previous dependence on cigarettes and almost identical questions to assess current dependence on e-cigs. More than 3,500 current users of e-cigs who were ex-cigarette smokers completed the Penn State Cigarette Dependence Index and the Penn State Electronic Cigarette Dependence Index.
Higher nicotine concentration in e-cig liquid, as well as use of advanced second-generation e-cigs, which deliver nicotine more efficiently than earlier “cigalikes,” predicted dependence. Consumers who had used e-cigs longer also appeared to be more addicted.
“However, people with all the characteristics of a more dependent e-cig user still had a lower e-cig dependence score than their cigarette dependence score,” Foulds said. “We think this is because they’re getting less nicotine from the e-cigs than they were getting from cigarettes.”
Although many regular users on e-cigarettes are trying to quit smoking, the Food and Drug Administration has not approved them for this use, and they cannot be marketed as a smoking cessation product.
“This is a new class of products that’s not yet regulated,” Foulds said. “It has the potential to do good and help a lot of people quit, but it also has the potential to do harm. Continuing to smoke and use e-cigarettes may not reduce health risks. Kids who have never smoked might begin nicotine addiction with e-cigs. There’s a need for a better understanding of these products.
“We don’t have long-term health data of e-cig use yet, but any common sense analysis says that e-cigs are much less toxic. And our paper shows that they appear to be much less addictive, as well. So in both measures they seem to have advantages when you’re concerned about health.”
The findings, which are published in Nicotine & Tobacco Research, also have implications for developing e-cigs for smoking cessation.
“We might actually need e-cigarettes that are better at delivering nicotine because that’s what’s more likely to help people quit,” Foulds said.
Previous research shows that nicotine replacement efficacy correlates with higher nicotine dose and faster delivery speed.
The new index used in the study is more modern than the most widely used dependence survey, the Fagerstrom Test for Nicotine Dependence. That scale was developed 25 years ago and does not reflect modern use of tobacco and nicotine products.
“People smoke fewer cigarettes today but are still clearly addicted, and the old scale — while still reasonably effective — was not designed to measure that,” Foulds said.
The new questionnaire also allows for cross-comparisons between different nicotine and tobacco products.
“Not only are e-cigs a booming industry, but new tobacco products are set to enter the market soon,” Foulds said. “Our questionnaire is designed to compare dependence across different products simply by substituting the different product name into the questionnaire in place of cigarettes.”
Additional researchers on this project are Susan Veldheer, research coordinator, Jessica Yingst, research assistant, and Shari Hrabovsky, research nurse practitioner, all at Penn State College of Medicine; Stephen J. Wilson and Travis T. Nichols, both at Penn State; and Thomas T. Eissenberg at Virginia Commonwealth University.
This work was initially funded by an internal grant from Penn State Social Science Research Institute and Cancer Institute, the National Institute on Drug Abuse of the National Institutes of Health and the Center for Tobacco Products of the U.S. Food and Drug Administration
– This is the Original Article as posted by Jennifer Abbasi on December 9, 2014 on http://news.psu.edu/story/337639/2014/12/09/research/e-cigarettes-less-addictive-cigarettes
Image: ©iStock Photo mauro_grigollo